Thymosin Alpha-1

Potential Benefits of Thymosin Alpha-1 Peptide

• Treatment for Sepsis: Research suggests Thymosin Alpha-1 (Tα1) has shown potential benefits in the treatment of sepsis. Specifically, it has been suggested that certain patient groups may be more likely to benefit from Tα1 immunotherapy [1], [2] and [3].
• Immune Modulation: According to research, Tα1 is noted for its immune-modulating properties. It has been found to have higher clinical benefit rates when used in conjunction with other treatments [4].
• Dental Applications: In studies, Tα1 has demonstrated both short-term and long-term benefits in the reimplantation of avulsed teeth [5].
• Broad Clinical Benefits: Since its first use in a clinical trial in 1985, a substantial amount of data has been produced supporting the potential clinical benefits of Tα1 [6].
• Cancer Therapy: Tα1 has been reappraised for its use in cancer therapy, with studies suggesting a higher clinical benefit rate and a trend towards its use in conjunction with other treatments [7].
• Treatment for Various Diseases: Research suggests the number of diseases that could potentially benefit from Tα1 treatment is growing, as it is a naturally occurring polypeptide [8].
• Treatment for Chronic Hepatitis B: Studies indicate the combined use of Tα1 and entecavir has shown benefits in the treatment of chronic hepatitis B [9].
• HIV-1 Treatment: Despite the consistent benefits for HIV-1 infected patients, more studies are needed concerning the use of Tα1 in HIV-1 infection [10].

References

[1] https://www.tandfonline.com/doi/ abs/10.1080/14712598.2018.1484104

[2] https://www.sciencedirect.com/science/ article/pii/S1201971214017500

[3] https://pubmed.ncbi.nlm.nih.gov/23327199/

[4] https://www.sciencedirect.com/science/ article/abs/pii/S0083672916300036

[5] https://pubmed.ncbi.nlm.nih.gov/18534287/

[6] https://nyaspubs.onlinelibrary.wiley.com/ doi/abs/10.1196/annals.1415.044

[7] https://www.frontiersin.org/journals/ oncology/articles/10.3389/fonc.2019.00873/full

[8] https://pubmed.ncbi.nlm.nih.gov/30063864/

[9] https://www.tandfonline.com/doi/ full/10.1517/14712598.2015.1007948

[10] https://pubmed.ncbi.nlm.nih.gov/28106477/